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- Annals of Indian Academy of Neurology
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影響因子：
0.572
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I S S N：
0972-2327
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出 版 社：
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出 版 地：
Indian
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出版國家：
Indian
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刊 期：
季刊
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創(chuàng)刊時間：
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語 種：
英文
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審稿周期：
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中科院分區(qū)：
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投稿命中率：
容易
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國外數(shù)據(jù)庫收錄：
IM
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中國收錄文章數(shù)：
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5年影響因子：
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研究領(lǐng)域：
臨床神經(jīng)病學(xué)
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官方鏈接：
http://www.annalsofian.org/
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投稿須知：
http://www.annalsofian.org/
期刊介紹：
Stroke is a major health problem world-wide and its burden has been rising in last few decades. Until now tissue plasminogen activator is only approved treatment for stroke. Angiogenesis plays a vital role for striatal neurogenesis after stroke. Administration of various growth factors in an early post ischemic phase, stimulate both angiogenesis and neurogenesis and lead to improved functional recovery after stroke. However vascular endothelial growth factors (VEGF) is the most potent angiogenic factor for neurovascularization and neurogenesis in ischemic injury can be modulated in different ways and thus can be used as therapy in stroke. In response to the ischemic injury VEGF is released by endothelial cells through natural mechanism and leads to angiogenesis and vascularization. This release can also be up regulated by exogenous administration of Mesenchymal stem cells, by various physical therapy regimes and electroacupuncture, which further potentiate the efficacy of VEGF as therapy in post stroke recovery. Recent published literature was searched using PubMed and Google for the article reporting on methods of up regulation of VEGF and therapeutic potential of growth factors in stroke.
