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醫(yī)學(xué)免費(fèi)論文:長(zhǎng)期口服“偏方”對(duì)支氣管哮喘重度及危重發(fā)作治療反應(yīng)的影響
【摘要】 目的 探討長(zhǎng)期口服“偏方”對(duì)支氣管哮喘重度及危重發(fā)作時(shí)治療反應(yīng)的影響。方法 重度及危重支氣管哮喘患者62例，其中服過(guò)“偏方”超過(guò)1年的患者30例作為觀察組，未服藥者32例作為對(duì)照組，對(duì)2組患者給予常規(guī)治療，并把治療前及治療3天后的心率(HR)、呼吸頻率(RR)、動(dòng)脈收縮壓(SP)、動(dòng)脈血?dú)夥治觥惭醴謮?PaO2)、二氧化碳分壓(PaCO2)、pH值〕進(jìn)行對(duì)照分析，治療1周后進(jìn)行療效評(píng)定。結(jié)果 2組治療3天后的HR、RR、SP及動(dòng)脈血?dú)饩^治療前有明顯改善(P<0.05)，但兩組相比觀察組較差(P<0.05)，1周后的有效率2組間差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 觀察組對(duì)治療的反應(yīng)差，考慮由長(zhǎng)期服用“偏方”所致，因此推廣及普及哮喘的長(zhǎng)期規(guī)范化管理是呼吸科各級(jí)醫(yī)生共同努力的目標(biāo)。
【關(guān)鍵詞】 支氣管哮喘;偏方;臨床觀察
Clinical observation of severe and critical bronchial asthma attacks due to
long-term oral administration of folk prescriptions
YANG Ning, SHANG Yulong, HAN Baohua, LUO Wei, LU Juan
(Department of Respiratory, The Third People′s Hospital of Xuzhou, Xuzhou, Jiangsu 221006, China)
Abstract： Objective To investigate the response to treatment and the prognosis of severe and critical bronchial asthma attacks due to long-term oral administration of folk prescriptions. Methods 62 patients with severe and critical bronchial asthma from Jan. 2006 to Dec. 2008 were selected, of whom 30 patients with a history of folk prescription administration for more than 1 year were designated as the observation group, while the other 32 patients who had not taken any folk medication served as the control group. Both groups underwent routine treatment and their data as to the heart rate (HR), respiration rate (RR), systolic pressure (SP), partial arterial oxygen tension (PaO2), partial pressure of carbon dioxide in arterial blood (PaCO2) and pH were collected and compared before and 3 days after the treatment. One week later, the therapeutic evaluation was conducted. Results 3 days later the treatment, the HR, RR, SP and arterial blood gases of both groups had marked improvement (P<0.05), but the results in the observation group were inferior to those in the control group (P<0.05). One week after treatment, compared with the contrast group, the effective rate in the observation group still had obvious statistics significance (P<0.05). Conclusion The reason for the poor treatment effect in the observation group is due to the long-term abuse of folk prescriptions. Therefore, it is the duty and goal of doctors at all levels to promote and popularize the long-term standardized management of asthma.
Key words： bronchial asthma; folk prescription; clinical observation醫(yī).學(xué).全.在.線m.gydjdsj.org.cn
支氣管哮喘(簡(jiǎn)稱(chēng)哮喘)是常見(jiàn)的慢性呼吸道疾病，近年來(lái)其患病率在全球范圍內(nèi)有逐年增加的趨勢(shì)。盡管全球哮喘防治創(chuàng)議(GINA)已公布多年，相當(dāng)一部分患者得到不同程度的控制，但在一些地區(qū)仍有一部分人迷信“偏方”，導(dǎo)致演進(jìn)為難治性哮喘，為臨床救治帶來(lái)一定的困難，病死率增高。為進(jìn)一步規(guī)范我國(guó)哮喘的診斷和治療，提高臨床醫(yī)生對(duì)此類(lèi)病例的認(rèn)識(shí)，現(xiàn)將2006年1月至2008年12月期間經(jīng)我科治療的此類(lèi)患者的觀察情況總結(jié)如下。
